|本期目录/Table of Contents|

[1]王莉,刘涛,丁新波,等.丝素-壳聚糖/聚氧化乙烯双层纳米纤维膜制备及其生物活性[J].浙江理工大学学报,2022,47-48(自科四):474-481.
 WANG Li,LIU Tao,DING Xinbo,et al.Preparation of silk fibroin chitosan/polyvinyl oxide  bilayer nanofiber membrane and its bioactivity[J].Journal of Zhejiang Sci-Tech University,2022,47-48(自科四):474-481.
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丝素-壳聚糖/聚氧化乙烯双层纳米纤维膜制备及其生物活性()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第47-48卷
期数:
2022年自科第四期
页码:
474-481
栏目:
出版日期:
2022-09-30

文章信息/Info

Title:
Preparation of silk fibroin chitosan/polyvinyl oxide  bilayer nanofiber membrane and its bioactivity
文章编号:
1673-3851 (2022) 07-0474-08
作者:
王莉刘涛丁新波李雅仇巧华王吉楠王寅
浙江理工大学,a.纺织科学与工程学院(国际丝绸学院);b.科技与艺术学院,杭州 310018
Author(s):
WANG Li LIU Tao DING Xinbo LI Ya QIU Qiaohua WANG Jinan WANG Yin
a. College of Textile Science and Engineering (International Institute of Silk); b. Keyi College, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
丝素蛋白壳聚糖双层纳米纤维膜静电纺丝生物活性
分类号:
TB332
文献标志码:
A
摘要:
以丝素蛋白(Silk fibroin, SF)、壳聚糖(Chitosan, CS)和聚氧化乙烯(Polyvinyl oxide, PEO)为原材料,利用静电纺丝技术制备SFCS/PEO双层纳米纤维膜;采用扫描电子显微镜、红外光谱等对SF CS/PEO双层纳米纤维膜的微观形貌结构进行表征,并分析了SF CS/PEO双层纳米纤维膜的溶胀度、水接触角和机械性能,并通过浸泡模拟体液考察了其体外生物活性。结果表明:SF CS/PEO双层纳米纤维膜呈现三维网络结构,在磷酸盐缓冲液中的溶胀度可达556%;SF层的水接触角为77.89°,CS/PEO层为47.45°;双层纳米纤维膜的断裂强度为4.35 MPa、断裂伸长率为25.52%、杨氏模量74.27 MPa;浸泡模拟体液后双层纳米纤维膜表面沉积了簇状羟基磷灰石,体现出较好的生物活性。因此,该丝素-壳聚糖/聚氧化乙烯双层纳米纤维膜有望应用于骨组织再生修复。

参考文献/References:

1 Zhang S, Xing M, Li B. Biomimetic layerbylayer selfassembly of nanofilms, nanocoatings, and 3D scaffolds for tissue engineering J . International Journal of Molecular Sciences, 2018, 19(6): 1641 - 1660.

2Kishan A P, CosgriffHernandez E M. Recent advancements in electrospinning design for tissue engineering applications: A reviewJ. Journal of Biomedical Materials Research Part A, 2017, 105(10): 2892 - 2905.
3] 黄予旸, 姜猛进. 静电纺丝技术在生物医用材料领域的应用[J. 合成纤维工业, 2019, 42(1): 64 - 70.
4] 张家盛, 吴刚, 邱江. 组织工程中细胞与生物材料相互作用研究进展[J. 生物工程学报, 2021, 37(8): 2668 - 2677.
5HernándezRangel A, MartinMartinez E S. Collagen based electrospun materials for skin wounds treatmentJ. Journal of biomedical materials research, 2021, 109(9): 1751 - 1764.
6] 刘, 齐磊, 左明星, . 天然生物材料在组织工程和再生医学中的应用[J. 医疗卫生装备, 2019, 40(3): 98 - 103.
7Jin S, Yang R, Chu C, et al. Topological structure of electrospun membrane regulates immune response, angiogenesis and bone regenerationJ. Acta Biomaterialia, 2021, 129(5): 148 - 158.
8Zhang X, Zhu D, Cheng Y, et al. Preparation and biocompatibility characterization of regenerated silk fibroin filmsJ. Journal of Macromolecular Science, 2021, 60(8): 603 - 615.
9Yang W, Xu H, Lan Y, et al. Preparation and characterisation of a novel silk fibroin/hyaluronic acid/sodium alginate scaffold for skin repairJ. International Journal of Biological Macromolecules, 2019, 130(2): 58 - 67.
10Zhao Y H, Niu C M, Shi J Q, et al. Novel conductive polypyrrole/silk fibroin scaffold for neural tissue repairJ. Neural Regeneration Research, 2018, 13(8): 1455 - 1464

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备注/Memo

备注/Memo:
收稿日期:2022-01-11
网络出版日期:2022-03-18
基金项目:国家自然科学基金项目(31900964)
作者简介:王莉(1996-),女,浙江温州人,硕士研究生,主要从事现代纺织技术及新产品开发的研究
通信作者:刘涛,E-mail:maggie_liu310@163.com
更新日期/Last Update: 2022-09-06