|本期目录/Table of Contents|

[1]陈鹏,王耐艳,郑莹莹.聚氧化乙烯@明胶纤维制备及其生物性能探究[J].浙江理工大学学报,2019,41-42(自科一):56-64.
 CHEN peng,WANG Naiyan,ZHENG Yingying.Preparation and biological properties of Chitosan PEO@Gelatin nanofibers[J].Journal of Zhejiang Sci-Tech University,2019,41-42(自科一):56-64.
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聚氧化乙烯@明胶纤维制备及其生物性能探究()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第41-42卷
期数:
2019年自科一期
页码:
56-64
栏目:
出版日期:
2018-12-15

文章信息/Info

Title:
Preparation and biological properties of Chitosan PEO@Gelatin nanofibers
文章编号:
1673-3851 (2019) 01-0056-09
作者:
陈鹏 王耐艳 郑莹莹
浙江理工大学,a.理学院;b.材料与纺织学院,杭州 310018
Author(s):
CHEN peng WANG Naiyan ZHENG Yingying
a.School of Sciences; b.School of Materials and Textiles, Zhejiang  Sci-Tech University, Hangzhou 310018, China
关键词:
壳聚糖明胶同轴电纺细胞培养
分类号:
Q28
文献标志码:
A
摘要:
为提高壳聚糖的可纺性和生物相容性进行了材料设计。通过在壳聚糖(CS)乙酸溶液中引入高度可纺性的聚氧化乙烯(PEO)来提高壳聚糖的可纺性,并以高度可纺性的明胶(GEL)作为核模板,通过同轴静电纺丝技术进一步提高壳聚糖的可纺性,并制备出核壳结构的壳聚糖聚氧化乙烯@明胶(CSPEO@GEL)纤维。纺丝实验结果显示,CS和GEL浓度对纤维成型有显著影响,最佳条件为:CS浓度为3%(W/V),CS和PEO质量比为4∶1,GEL浓度为41%(W/V);扫描电镜(SEM)和透射电镜(TEM)显示CSPEO@GEL纳米纤维表面均匀光滑,具有核壳结构,内径约为100 nm,外径约为150 nm;亲水性测试结果表明,亲水性较好的PEO和GEL能够明显提高CS的亲水性;骨肉瘤细胞MG63培养过程中,CSPEO@GEL纤维呈现出良好的生物相容性。所制备的CSPEO@GEL纤维材料在骨组织工程上具有潜在的研究价值。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期: 2017-03-22
网络出版日期: 2018-06-02
基金项目: 国家自然科学基金项目(51603187);浙江省自然科学基金项目(LY15E030011)
作者简介: 陈鹏(1992-),男,江苏南京人,硕士研究生,主要从事生物复合材料的制备以及生物性能方面的研究
通信作者: 郑莹莹,E-mail:zhengyy1718@zstu.edu.cn
更新日期/Last Update: 2019-03-13