|本期目录/Table of Contents|

[1]杜志游,周昀茜,董温昕.植物病毒纳米颗粒在医学领域中的应用[J].浙江理工大学学报,2022,47-48(自科一):104-114.
 DU Zhiyou,ZHOU Yunqian,DONG Wenxin.Application of plant virus nanoparticles in tumor therapy[J].Journal of Zhejiang Sci-Tech University,2022,47-48(自科一):104-114.
点击复制

植物病毒纳米颗粒在医学领域中的应用()
分享到:

浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第47-48卷
期数:
2022年自科第一期
页码:
104-114
栏目:
出版日期:
2022-01-31

文章信息/Info

Title:
Application of plant virus nanoparticles in tumor therapy
文章编号:
1673-3851 (2022) 01-0109-06
作者:
杜志游周昀茜董温昕
浙江理工大学生命科学与医药学院,杭州 310018
Author(s):
DU Zhiyou ZHOU Yunqian DONG Wenxin
College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
植物病毒纳米颗粒成像疫苗药物传递
分类号:
TS195-644 S432-41
文献标志码:
A
摘要:
植物病毒粒子作为纳米级颗粒,具有在植物细胞内积累水平高、再生成本低、纯化工艺简单及对人体安全等优点,是一种理想的天然纳米材料。随着生物纳米技术的发展,植物病毒纳米颗粒在医学领域展现出越来越大的应用潜力,本文围绕靶向传递药物、分子成像和疫苗制备综述了植物病毒纳米颗粒在医学领域的研究进展和应用。

参考文献/References:

[1] Afrooz H, Ahmadi F, Fallahzadeh F, et al. Design and characterization of paclitaxelverapamil coencapsulated PLGA nanoparticles: potential system for overcoming Pglycoprotein mediated MDR[J]. Journal of Drug Delivery Science and Technology, 2017, 41: 174-181.
[2] Cho K J, Wang X, Nie S M, et al. Therapeutic nanoparticles for drug delivery in cancer[J]. Clinical Cancer Research, 2008, 14(5): 1310-1316.
[3] Kaiser C R, Flenniken M L, Gillitzer E, et al. Biodistribution studies of protein cage nanoparticles demonstrate broad tissue distribution and rapid clearance in vivo[J]. International Journal of Nanomedicine, 2007, 2(4): 715-733.
[4] Le D H T, Lee K L, Shukla S, et al. Potato virus X, a filamentous plant viral nanoparticle for doxorubicin delivery in cancer therapy[J]. Nanoscale, 2017, 9(6): 2348-2357.
[5] Czapar A E, Zheng Y R, Riddell I A, et al. Tobacco mosaic virus delivery of phenanthriplatin for cancer therapy[J]. Acs Nano, 2016, 10(4): 4119-4126.
[6] 李凯, 张金玲, 王倩, 等. 病毒纳米颗粒在医学领域的潜在应用[J]. 生物医学工程杂志, 2014, 31(3): 718-722.
[7] Alemzadeh E, Dehshahri A, Izadpanah K, et al. Plant virus nanoparticles: novel and robust nanocarriers for drug delivery and imaging[J]. Colloids and Surfaces BBiointerfaces, 2018, 167: 20-27.
[8] Allen T M, Cullis P R. Drug delivery systems: entering the mainstream[J]. Science, 2004, 303(5665): 1818-1822.
[9] Hashizume H, Baluk P, Morikawa S, et al. Openings between defective endothelial cells explain tumor vessel leakiness[J]. The American Journal of Pathology, 2000, 156(4): 1363-1380.
[10] Maeda H, Wu J, Sawa T, et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review[J]. Journal of Controlled Release, 2000, 65(1/2): 271-284.

相似文献/References:

[1]雷容,徐江晖,周文翠,等.多孔丝素颗粒的可控制备及药物负载研究[J].浙江理工大学学报,2018,39-40(自科1):37.
 LEI Rong,XU Jianghui,ZHOU Wencui,et al.Sizecontrolled preparation of porous silk fibroin particle used as drug carrier[J].Journal of Zhejiang Sci-Tech University,2018,39-40(自科一):37.

备注/Memo

备注/Memo:
收稿日期: 2021-02-24
网络出版日期:2021-07-02
基金项目:浙江省新苗人才计划项目(2019R406013)
作者简介:杜志游(1978-),男,浙江温州人,教授,博士,主要从事植物病毒学方面的研究
更新日期/Last Update: 2022-03-08