|本期目录/Table of Contents|

[1]张立,刘涛,张丽香,等.PEO/SA生物活性玻璃支架的制备和生物活性研究[J].浙江理工大学学报,2018,39-40(自科3):299-303.
 ZHANG Li,LIU Tao,ZHANG Lixiang,et al.Preparation and bioactivity of bioactive glass scaffold based on PEO/SA[J].Journal of Zhejiang Sci-Tech University,2018,39-40(自科3):299-303.
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PEO/SA生物活性玻璃支架的制备和生物活性研究()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第39-40卷
期数:
2018年自科3期
页码:
299-303
栏目:
出版日期:
2018-05-19

文章信息/Info

Title:
Preparation and bioactivity of bioactive glass scaffold based on PEO/SA
文章编号:
1673-3851 (2018) 05-0299-05
作者:
张立刘涛张丽香訾园兴丁新波
浙江理工大学,a.材料与纺织学院;b.科技与艺术学院,杭州 310018
Author(s):
ZHANG Li LIU Tao ZHANG Lixiang ZI Yuanxing DING Xinbo
a.College of Materials and Textiles; b.Keyi College, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
聚氧化乙烯海藻酸钠静电纺丝交联生物活性玻璃
分类号:
TQ127.2
文献标志码:
A
摘要:
将生物活性玻璃(Bioactive glass, BG)加入聚氧化乙烯(PEO)/海藻酸钠(SA)混合水溶液中,利用静电纺丝构建生物活性玻璃纤维支架,并将纤维膜浸泡在六亚甲基二异氰酸酯(HMDI)的甲苯溶液和氯化钙(CaCl2)水溶液中交联处理,进一步将交联后的纤维膜在模拟体液(Simulated body fluid, SBF)中浸泡1、3、5 d和7 d;通过扫描电子显微镜(SEM)、能谱仪(EDS)和X射线衍射仪(XRD)对其形貌结构、元素组成和晶体结构进行表征分析。研究结果表明:在交联剂中加入2%二月桂酸二丁基锡(DBTDL)作为催化剂使得纤维膜在模拟体液浸泡7 d后仍能保持纤维结构,并伴随羟基磷灰石的生成,因此PEO/SA纳米纤维膜通过上述方法交联处理后具有较好的耐水性能,并具有良好的生物活性。

参考文献/References:

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[8] 谢红,卢华,黄华,等.载药聚乙烯醇/海藻酸钠静电纺丝纤维的改性及其药物体外释放研究[J].第三军医大学学报,2011,33(23):2485-2489.
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备注/Memo

备注/Memo:
收稿日期: 2017-11-07
网络出版日期: 2018-01-06
基金项目: 国家自然科学基金项目(LY16E020012);浙江省自然科学基金项目(Y201534618)
作者简介: 张立(1994-),男,湖北孝感人,硕士研究生,主要从事现代纺织技术、新产品方面的研究与开发
通信作者: 丁新波,E-mail:dxblt@zstu.edu.cn
更新日期/Last Update: 2018-06-19