|本期目录/Table of Contents|

[1]刘欣,熊杰.再生丝素/明胶聚己内酯皮芯结构纳米纤维膜的制备及生物性能研究[J].浙江理工大学学报,2014,31-32(自科6):621-625.
 LIU Xin,XIONG Jie.Study on Preparation and Biological Properties of Nanofiber Membrane with Regenerated Silk Fibroin/Gelatin Polycaprolactone Skin core Structure[J].Journal of Zhejiang Sci-Tech University,2014,31-32(自科6):621-625.
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再生丝素/明胶聚己内酯皮芯结构纳米纤维膜的制备及生物性能研究()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第31-32卷
期数:
2014年自科6期
页码:
621-625
栏目:
纺织与服装工程
出版日期:
2014-11-10

文章信息/Info

Title:
Study on Preparation and Biological Properties of Nanofiber Membrane with Regenerated Silk Fibroin/Gelatin Polycaprolactone Skin core Structure
文章编号:
1673-3851 (2014) 06-0621-05
作者:
刘欣 熊杰
浙江理工大学, a. 材料与纺织学院; b. 先进纺织材料与制备技术教育部重点实验室, 杭州 310018
Author(s):
LIU Xin XIONG Jie
a. School of Materials and Textiles; b. Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Ministry of Education, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
丝素 明胶 聚己内酯 同轴静电纺丝 皮芯结构 生物相容性
分类号:
TS102.1
文献标志码:
A
摘要:
利用同轴静电纺丝技术,制备以丝素(SF)/明胶(GE)共混物为皮层,聚己内酯(PCL)为芯层的复合纳米纤维膜。研究不同芯层浓度对复合纳米纤维膜形貌、孔径、力学性能和生物相容性的影响。结果表明:所制备的SF/GE PCL复合纳米纤维表面光滑且有明显的皮芯结构,随着芯层浓度由4%增大到10%,复合纳米纤维的平均直径从256 nm增大到941 nm,纤维膜的平均孔径从0.576 μm增大到1.018 μm,纤维膜的断裂强度和断裂应变增大,人皮肤成纤维细胞能在皮芯结构纳米纤维膜上黏附、生长和增殖。

参考文献/References:

[1] Kasoju N, Bhonde R R, Bora U. Fabrication of a novel micronano fibrous nonwoven scaffold with Antheraea assama silk fibroin for use in tissue engineering[J]. Materials Letters, 2009, 63(28): 2466-2469.
[2] Schnerider A, Wang X Y, Kaplan D L. et al. Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing[J]. Acta Biomaterials, 2009, 5(7): 2570-2578.
[3] Yin B G, Zhang Y Z, Bao W W, et al. Study on the properties of the electrospun silk fibroin/gelatin blend nanofibers for scaffolds[J]. Journal of Applied Polymer Science, 2009, 111(3): 1471-1477.
[4] Zhang Y Z, Ouyang H, Lim C T, et al. Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds[J]. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2005, 72(1): 156-165.
[5] 丁彬, 俞建勇. 静电纺丝与纳米纤维[M]. 北京: 中国纺织出版社, 2011: 83-85.
[6] Sun Z C, Zussman E, Yarin A L, et al. Compound coreshell polymer nanofibers by coelectrospinning[J]. Advanced Materials, 2003, 15(22): 1929-1932.
[7] 王曙东, 尹桂波, 吴佳林, 等. 静电纺再生丝素/明胶纳米纤维的结构与性能[J]. 纺织学报, 2008, 29(3): 1-8
[8] 徐安长, 赵静娜, 潘志娟, 等. 静电纺聚乳酸纤维毡的微观结构及力学行为[J]. 纺织学报, 2007, 28(7): 4-7

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备注/Memo

备注/Memo:
收稿日期: 2014-01-08
基金项目: 国家自然科学基金(11272289);浙江省重点科技创新团队计划资助(2011R50003)
作者简介: 刘欣(1988-),女,河南泌阳人,硕士研究生。主要从事新纤维材料及功能性纤维材料的研究
通信作者: 熊杰,E-mail:jxiong@zstu.edu.cn
更新日期/Last Update: 2014-11-19