|本期目录/Table of Contents|

[1]闵靖舒,夏超义.中药活性成分靶向调控铁死亡治疗相关疾病的研究进展[J].浙江理工大学学报,2026,55-56(自科六):814-823.
 MIN Jingshu,XIAChaoyi.Research progress on the targeted regulation of ferroptosis by bioactive constituents of traditional Chinese medicine for disease therapy[J].Journal of Zhejiang Sci-Tech University,2026,55-56(自科六):814-823.
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中药活性成分靶向调控铁死亡治疗相关疾病的研究进展()

浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
55-56
期数:
2026年自科第六期
页码:
814-823
栏目:
出版日期:
2026-11-10

文章信息/Info

Title:
Research progress on the targeted regulation of ferroptosis by bioactive constituents of traditional Chinese medicine for disease therapy
文章编号:
1673-3851(2026) 11-0814-10
作者:
闵靖舒; 夏超义
浙江理工大学生命科学与医药学院 ,杭州 310018
Author(s):
MIN Jingshu; XIAChaoyi
College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
铁死亡; 中药活性成分 ; 防御系统; 疾病 ; 治疗策略
分类号:
R285.5;R329.2
文献标志码:
A
摘要:
铁死亡是一种由铁依赖性脂质过氧化驱动的细胞死亡形式 ,在形态与生化特征上区别于凋亡、坏死等其他细胞死亡方式 。铁死亡的核心调控机制以脂质过氧化为关键驱动力 ,依赖四大防御系统的协同作用 , 同时与铁代谢、脂质代谢等通路相互调控密切相关 。铁死亡调控网络的功能紊乱已被证实与肿瘤、心血管疾病、神经退行性疾病等多种重大疾病的发生发展及病理进程紧密相关 ; 中药活性成分是从中药材中提取得到的 ,具有明确的化学结构或潜在生物活性的化学物质 。该研究围绕铁死亡的核心机制、铁死亡与疾病的联系以及中药活性成分通过靶向调节铁死亡治疗相关疾病的研究进展展开系统综述 , 旨在为开发靶向铁死亡的新型中药活性成分药物提供理论依据和方向参考。

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备注/Memo

备注/Memo:
收稿日期 : 2025-10-24 网络出版日期 : 2026-06-02作者简介 : 闵靖舒(2001— ) ,女 ,河南信阳人 ,硕士研究生 ,主要从事生物化学和分子生物学方面的研究。通信作者: 夏超义,E-mail:xiacy834@zstu. edu. cn
更新日期/Last Update: 2026-11-09