[1]刘文金,曹小冬.HSP90抑制剂前药设计及合成[J].浙江理工大学学报,2023,49-50(自科五):604-611.
　LIU Wenjin,CAO Xiaodong.Design and synthesis of HSP90 inhibitor prodrugs[J].Journal of Zhejiang Sci-Tech University,2023,49-50(自科五):604-611.

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HSP90抑制剂前药设计及合成()

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［2］Sidera K, Patsavoudi E. HSP90 inhibitors: Current development and potential in cancer therapy［J］. Recent Patents on Anti-Cancer Drug Discovery, 2013, 9(1): 1-20.

［3］Alarcon S V, Mollapour M, Lee M J, et al. Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy［J］. Current Molecular Medicine, 2012, 12(9): 1125-1141.

［4］张钟元, 阎爱侠. Hsp90抑制剂的研究进展［J］. 中国医药生物技术, 2021, 16(1): 41-50.

［5］Shrestha L, Bolaender A, Patel H J, et al. Heat shock protein (HSP) drug discovery and development: Targeting heat shock proteins in disease［J］. Current Topics in Medicinal Chemistry, 2016, 16(25): 2753-2764.

［6］Liu N X, Chen Q H, Zhang Q Q, et al. The application of prodrug-based drug delivery strategy in anticancer drugs［J］. Current Topics in Medicinal Chemistry, 2021, 21(24): 2184-2204.

［7］Zawilska J B, Wojcieszak J, Olejniczak A B. Prodrugs: A challenge for the drug development［J］. Pharmacological Reports, 2013, 65(1): 1-14.

［8］Zhang T, Yang X R, Xu W P, et al. Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy［J］. Cancer Biology & Medicine, 2021, 18(3): 693-704.

［9］Daneri-Becerra C, Galigniana M D. The Hsp90-binding immunophilin FKBP52 enhances neurodifferentiation and neuroregeneration in murine models［J］. Neural Regeneration Research, 2022, 17(3): 555-556.

［10］林智才, 陈燕丽, 苏小清, 等. Hsp90抑制剂减弱肝癌耐药细胞株对索拉非尼诱导铁死亡的耐受性［J］. 现代肿瘤医学, 2022, 30(21): 3862-3868.

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