|本期目录/Table of Contents|

[1]徐盼举,邢赟,许为中,等.刚性基底表面图案化氧化石墨烯对细胞粘附行为调控[J].浙江理工大学学报,2017,37-38(自科6):778-784.
　XU Panju,XING Yun,XU Weizhong,et al.Regulation of Cell Adhesion by Surface Patterning  Graphene Oxide on Rigid Substrates[J].Journal of Zhejiang Sci-Tech University,2017,37-38(自科6):778-784.
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刚性基底表面图案化氧化石墨烯对细胞粘附行为调控()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第37-38卷
期数:
2017年自科6期
页码:
778-784
栏目:
出版日期:
2017-11-10

文章信息/Info

Title:
Regulation of Cell Adhesion by Surface Patterning  Graphene Oxide on Rigid Substrates
文章编号:
1673-3851 (2017) 06-0778-07
作者:
徐盼举; 邢赟; 许为中; 黄敏; 刘爱萍
浙江理工大学，a.物理系；b.光电材料与器件中心,杭州 310018
Author(s):
XU Panju;  XING Yun;  XU Weizhong;  Huang Min;  LIU Aiping
a.Department of Physics, b.Center for Optoelectronics Materials and Devices, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
氧化石墨烯; 阵列材料; 刚性基底; 细胞选择性粘附
分类号:
Q689
文献标志码:
A
摘要:
生物材料的物理化学性质（如刚度、粗糙度、亲疏水性等）对细胞的粘附、增殖、迁移、分化、凋亡等一系列生命活动会产生重要的影响。此外，对材料进行图案化设计也是调控细胞生命活动的一种有效手段。采用软光刻的方法，以聚二甲基硅氧烷为印章，通过调节压力，获得图案较为规整的氧化石墨烯(GO)阵列。在优化的压力条件下，成功将GO阵列转移至硅、类金刚石膜、氧化铟锡玻璃三种刚性基底表面。利用基底材料与GO材料性能的差异，实现了对神经细胞(PC12)选择性粘附的有效调控。研究结果表明：与刚性基底相比，硬度较小且亲水的GO表面更能有效促进PC12细胞的选择性粘附和增殖。GO阵列表面越大，其表面粘附的细胞密度越大。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期： 2017－04－27
网络出版日期： 2017-08-07
基金项目： 国家自然科学基金项目(51272237, 51572242)；浙江省自然科学基金项目(LY16E020011)；浙江理工大学521人才培养计划
作者简介： 徐盼举(1991-)，男，河北邯郸人，硕士研究生，主要从事无机纳米材料合成及应用方面的研究
通信作者： 刘爱萍，E-mail：aipingwz@163.com
更新日期/Last Update: 2017-11-16