|本期目录/Table of Contents|

[1]王波,刘涛,黄睿,等.多层结构生物活性玻璃的制备及其止血性能研究[J].浙江理工大学学报,2026,55-56(自科四):431-442.
　WANGBo,LIUTao,HUANGRui,et al.A study on the preparation of multilayered bio active glass and Its hemostatic properties[J].Journal of Zhejiang Sci-Tech University,2026,55-56(自科四):431-442.
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多层结构生物活性玻璃的制备及其止血性能研究()

浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
55-56
期数:
2026年自科第四期
页码:
431-442
栏目:
出版日期:
2026-07-10

文章信息/Info

Title:
A study on the preparation of multilayered bio active glass and Its hemostatic properties
文章编号:
1673-3851(2026) 07-0431-12
作者:
王波; 刘涛; 黄睿; 丁新波; 祝国成
浙江理工大学纺织科学与工程学院(国际丝绸学院)， 杭州310018
Author(s):
WANGBo; LIUTao; HUANGRui; DINGXinbo; ZHUGuocheng
College of Textile Science and Engineering(International Institute of Silk) ,Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
铈生物玻璃 ; 聚多巴胺; ε-聚赖氨酸 ; 生物活性 ; 抗菌性能; 止血性能
分类号:
TB332
文献标志码:
A
摘要:
针对现有止血材料普遍存在适用伤口类型有限且易引起感染的问题 , 以掺铈生物玻璃(Ce-BG)纳米颗粒为基体 ,在其表面依次包覆聚多巴胺(PDA)与 ε-聚赖氨酸(EPL) , 构建具有多层结构的生物活性玻璃 Ce-BG@ PDE纳米颗粒 ;对改性前后的样品进行形貌结构表征 , 并系统评价其润湿行为、体外生物活性、抗菌性能及止血效果 。结果表明 :Ce-BG@PDE的水接触角显著下降 ,亲水性能明显提升 ;在模拟体液中浸泡时 ,其羟基磷灰石形成速率高于未改性 Ce-BG;对金黄色葡萄球菌和大肠埃希菌的抑菌率均超过 98.9% ;体外凝血时间为(76.0±2.0) s,凝血指数为 16.9% ,血液吸附能力强且溶血率低 ,红细胞聚集显著 。该文制备的 Ce-BG@PDE在润湿性、生物活性、抗菌及止血性能方面均有显著提升 ,展现出作为控制出血与伤口感染材料的潜在应用价值。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期 : 2025-11-26 网络出版日期 : 2026-01-27基金项目 : 浙江省“尖兵”“领雁”研发攻关计划项目(2023C1194) ; 国家自然科学基金项目(31900964)作者简介 : 王 波 (2001— ) ,女 ,河南南阳人 ,硕士研究生 ,主要从事生物纳米材料的研究。通信作者: 丁新波,E-mail: dxblt@zstu. edu. cnitspotentialapplication valueasamaterialforcontrollingbleeding and wound infection.Keywords: cerium-doped bioactive glass; polydopamine; ε-poly-L-lysine; bioactivity; antibacterial properties; hemostaticproperties
更新日期/Last Update: 2026-07-05