[1]杨丽萍,曹小冬.2-磺酸-4-硫代丁酸类抗体-药物偶联物连接子的合成[J].浙江理工大学学报,2023,49-50(自科三):374-378.
　YANG Liping,CAO Xiaodong.Synthesis of 2-sulfonic acid-4-thiobutanoic acid antibody drug conjugate linker[J].Journal of Zhejiang Sci-Tech University,2023,49-50(自科三):374-378.

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2-磺酸-4-硫代丁酸类抗体-药物偶联物连接子的合成()

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［3］Fu Z W, Li S J, Han S F, et al. Antibody drug conjugate: the “biological missile” for targeted cancer therapy［J］. Signal Transduction and Targeted Therapy, 2022, 7(4): 1066-1090.

［4］Moore K N, Martin L P, O’Malley D M, et al. Safety and activity of mirvetuximab soravtansine (IMGN 853), a folate receptor alpha-targeting antibody-drug conjugate, in platinum-resistant ovarian, fallopian tube, or primary peritoneal cancer: a phase I expansion study［J］. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2017, 35(10): 1112-1118.

［5］Whiteman K R, Johnson H A, Sun X X, et al. Anti-tumor activity and pharmacokinetics of the anti-FOLR1-maytansinoid conjugate IMGN853 is maintained over a wide range of maytansinoid-to-antibody ratios［J］. Cancer Research, 2012, 72(8): 4628-4628.

［6］Salomon P L, Singh R. Sensitive ELISA method for the measurement of catabolites of antibody-drug conjugates (ADCs) in target cancer cells［J］. Molecular Pharmaceutics, 2015, 12(6): 1752-1761.

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［9］Zhao R Y, Wilhelm S D, Audette C, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates［J］. Journal of Medicinal Chemistry, 2011, 54(10): 3606-3623.

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