|本期目录/Table of Contents|

[1]郑洁,刘涛,丁新波,等.SF/GO纳米纤维复合支架的制备及体外生物活性[J].浙江理工大学学报,2022,47-48(自科二):147-152.
 ZHENG Jie,LIU Tao,DING Xinbo,et al.Preparation and in vitro biological activity of SF/GO nanofiber composite scaffold[J].Journal of Zhejiang Sci-Tech University,2022,47-48(自科二):147-152.
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SF/GO纳米纤维复合支架的制备及体外生物活性()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第47-48卷
期数:
2022年自科第二期
页码:
147-152
栏目:
出版日期:
2022-03-10

文章信息/Info

Title:
Preparation and in vitro biological activity of SF/GO nanofiber composite scaffold
文章编号:
1673-3851 (2022) 03-0147-06
作者:
郑洁刘涛丁新波王吉楠王寅
浙江理工大学,a.纺织科学与工程学院(国际丝绸学院
Author(s):
ZHENG JieLIU TaoDING XinboWANG JinanWANG Yin
a. College of Textile Science and Engineering (International Institute of Silk); b.Keyi College, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
复合支架丝素蛋白氧化石墨烯静电纺丝体外生物活性
分类号:
TS195-644
文献标志码:
A
摘要:
为了获得良好生物相容性和导电性能的复合支架,以丝素蛋白(SF)为基材,自制氧化石墨烯(GO)为添加剂,利用静电纺丝技术制备SF/GO纳米纤维复合支架;采用扫描电子显微镜、傅里叶变换红外光谱(FTIR)、数字万用表对复合支架的微观形貌、分子结构、导电性能以及体外生物活性进行了表征,结果表明:当GO与SF质量比为1-5/100时,纳米纤维复合支架材料的导电性最佳达到1-3 kΩ;模拟体液处理后,样品表面沉积呈现出球状羟基磷灰石,体现出良好的生物相容性。

参考文献/References:

[1] 李勐, 郭保林. 导电高分子生物材料在组织工程中的应用[J]. 科学通报, 2019, 64(23): 2410-2424.
[2] Rajesh, Ahuja T, Kumar D. Recent progress in the development of nanostructured conducting polymers/nanocomposites for sensor applications[J].Sensors and Actuators B: Chemical, 2009, 136(1): 275-286.
[3] 熊莹, 许燕, 周建平,等. 组织工程研究中的电活性生物材料[J]. 中国组织工程研究, 2019, 23(34): 5523-5530.
[4] Xu J, Wang D X, Yuan Y, et al. Polypyrrole/reduced graphene oxide coated fabric electrodes for supercapacitor application[J]. Organic Electronics, 2015, 24(5): 153-159.
[5] GuiBo Y, YouZhu Z, ShuDong W, et al. Study of the electrospun PLA/silk fibroingelatin composite nanofibrous scaffold for tissue engineering[J]. Journal of Biomedical Materials Research Part A, 2010, 93(1): 158-163.
[6] Wang S D, Zhang K Q. Electrogelation and rapid prototyping of Bombyx mori silk fibroin[J]. Materials Letters, 2016, 169(15): 5-9.
[7] Jalali Monfared M, Nasirinezhad F, EbrahimiBarough S, et al. Transplantation of miR219 overexpressed human endometrial stem cells encapsulated in fibrin hydrogel in spinal cord injury[J]. Journal of Cellular Physiology, 2019, 234(10): 18887-18896.
[8] Farokhi M, Mottaghitalab F, Samani S, et al. Silk fibroin/hydroxyapatite composites for bone tissue engineering[J]. Biotechnology Advances, 2018, 36(1): 68-91.
[9] 张超. 丝素蛋白/石墨烯仿生复合材料的结构设计与性能[D]. 上海: 东华大学, 2018: 24-85.
[10] 赵静, 张红. 氧化石墨烯的可控还原及表征[J]. 化工进展, 2015, 34(9): 3383-3387.

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备注/Memo

备注/Memo:
收稿日期:2021-03-25
网络出版日期:2021-05-18
基金项目:国家自然科学基金项目(31900964);浙江省自然科学基金项目(KY2019002)
作者简介:郑洁(1996-),女,浙江衢州人,硕士研究生,主要从事生物医用纺织品方面的研究
通信作者:刘涛,E-mail:maggie_liu310@163.com
更新日期/Last Update: 2022-03-09