|本期目录/Table of Contents|

[1]陈鹏,王耐艳,郑莹莹.聚氧化乙烯@明胶纤维制备及其生物性能探究[J].浙江理工大学学报,2019,41-42(自科一):56-64.
　CHEN peng,WANG Naiyan,ZHENG Yingying.Preparation and biological properties of Chitosan PEO@Gelatin nanofibers[J].Journal of Zhejiang Sci-Tech University,2019,41-42(自科一):56-64.
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聚氧化乙烯@明胶纤维制备及其生物性能探究()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第41-42卷
期数:
2019年自科一期
页码:
56-64
栏目:
出版日期:
2018-12-15

文章信息/Info

Title:
Preparation and biological properties of Chitosan PEO@Gelatin nanofibers
文章编号:
1673-3851 (2019) 01-0056-09
作者:
陈鹏;  王耐艳;  郑莹莹
浙江理工大学，a.理学院；b.材料与纺织学院，杭州 310018
Author(s):
CHEN peng;  WANG Naiyan;  ZHENG Yingying
a.School of Sciences; b.School of Materials and Textiles, Zhejiang  Sci-Tech University, Hangzhou 310018, China
关键词:
壳聚糖; 明胶; 同轴电纺; 细胞培养
分类号:
Q28
文献标志码:
A
摘要:
为提高壳聚糖的可纺性和生物相容性进行了材料设计。通过在壳聚糖（CS）乙酸溶液中引入高度可纺性的聚氧化乙烯（PEO）来提高壳聚糖的可纺性，并以高度可纺性的明胶（GEL）作为核模板，通过同轴静电纺丝技术进一步提高壳聚糖的可纺性，并制备出核壳结构的壳聚糖聚氧化乙烯@明胶（CSPEO@GEL）纤维。纺丝实验结果显示，CS和GEL浓度对纤维成型有显著影响，最佳条件为：CS浓度为3%（W/V），CS和PEO质量比为4∶1，GEL浓度为41%（W/V）；扫描电镜（SEM）和透射电镜（TEM）显示CSPEO@GEL纳米纤维表面均匀光滑，具有核壳结构，内径约为100 nm，外径约为150 nm；亲水性测试结果表明，亲水性较好的PEO和GEL能够明显提高CS的亲水性；骨肉瘤细胞MG63培养过程中，CSPEO@GEL纤维呈现出良好的生物相容性。所制备的CSPEO@GEL纤维材料在骨组织工程上具有潜在的研究价值。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期： 2017-03-22
网络出版日期： 2018-06-02
基金项目： 国家自然科学基金项目(51603187)；浙江省自然科学基金项目(LY15E030011)
作者简介： 陈鹏(1992-)，男，江苏南京人，硕士研究生，主要从事生物复合材料的制备以及生物性能方面的研究
通信作者： 郑莹莹，E-mail：zhengyy1718@zstu.edu.cn
更新日期/Last Update: 2019-03-13