|本期目录/Table of Contents|

[1]王小飞,石卓兴,谭淑敏,等.家蚕蛋白亚细胞定位预测模型的构建及其初步应用[J].浙江理工大学学报,2015,33-34(自科2):238-243.
　WANG Xiao fei,SHI Zhuo xing,TAN Shu min,et al.Modeling and Preliminary Application of Sub cellular Localization Prediction Model for Proteins of Bombyx Mori[J].Journal of Zhejiang Sci-Tech University,2015,33-34(自科2):238-243.
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家蚕蛋白亚细胞定位预测模型的构建及其初步应用()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第33-34卷
期数:
2015年自科2期
页码:
238-243
栏目:
(自科)生物与生命科学
出版日期:
2015-03-10

文章信息/Info

Title:
Modeling and Preliminary Application of Sub cellular Localization Prediction Model for Proteins of Bombyx Mori
文章编号:
1673-3851 (2015) 02-0238-06
作者:
王小飞;  石卓兴;  谭淑敏;  李杰;  张耀洲;  于威;  陈剑清;  舒特俊
浙江理工大学生命科学学院生物化学研究所, 杭州 310018
Author(s):
WANG Xiaofei;  SHI Zhuoxing;  TAN Shumin;  LI Jie;  ZHANG Yaozhou;  YU Wei;  CHEN Jianqing;  SHU Tejun
Institute of Biochemistry, School of Life Science, Zhejiang Sci-Tech University, Hangzhou 310018, China
关键词:
家蚕;  亚细胞定位预测;  支持向量机;  P10蛋白
分类号:
TP399
文献标志码:
A
摘要:
为研究家蚕蛋白及家蚕杆状病毒蛋白的亚细胞定位并提高预测模型的特异性和准确率,构建了家蚕蛋白亚细胞定位预测模型,并将该模型初步应用于家蚕核型多角体病毒(BmNPV) P10蛋白的亚细胞定位预测中。结果表明,总体预测准确率在不分段时为60.6%,分两段、三段和四段时分别为78.9%、78.4%和80.6%;对BmNPV P10蛋白的预测结果为宿主细胞核,通过免疫细胞荧光实验对预测结果进行验证,结果表明预测结果与实际相符。因此,采用分段的方法能够提高预测准确率,且家蚕病毒蛋白可以利用其宿主家蚕蛋白亚细胞定位预测模型进行亚细胞定位。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期： 2014-03-12
基金项目： 国家高技术发展计划“863”项目(2011AA100603)
作者简介： 王小飞(1987-),男,山东枣庄人,硕士研究生,主要从事生物反应器与蛋白组学方面的研究
通信作者： 舒特俊,E-mail:petershu@126.com
更新日期/Last Update: 2015-03-24