|本期目录/Table of Contents|

[1]刘建军,郑世睿,姚舒婷,等.可逆交联聚电解质微胶囊的制备及表征[J].浙江理工大学学报,2017,37-38(自科4):587-591.
 LIU Jianjun,ZHENG Shirui,YAO Shuting,et al.Preparation and Characterization of ReversibleCrosslinked Polyelectrolyte Microcapsules[J].Journal of Zhejiang Sci-Tech University,2017,37-38(自科4):587-591.
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可逆交联聚电解质微胶囊的制备及表征()
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浙江理工大学学报[ISSN:1673-3851/CN:33-1338/TS]

卷:
第37-38卷
期数:
2017年自科4期
页码:
587-591
栏目:
出版日期:
2017-07-10

文章信息/Info

Title:
Preparation and Characterization of ReversibleCrosslinked Polyelectrolyte Microcapsules
文章编号:
1673-3851 (2017) 04-0587-05
作者:
刘建军郑世睿姚舒婷彭志勤万军民王秉胡智文
1.浙江理工大学材料与纺织学院,杭州 310018;2. 山东英利实业有限公司,山东潍坊 262700
Author(s):
LIU Jianjun ZHENG Shirui YAO Shuting PENG Zhiqin WAN Junmin WANG Bing HU Zhiwen
1.College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou 310018, China;2. Shandong Yingli Industrial Co.,Ltd., Weifang 262700, China
关键词:
微胶囊缓释模板法层层自组装可逆交联
分类号:
TB34
文献标志码:
A
摘要:
微胶囊在医药、食品、化妆品、日用品等行业都有重要应用,其中作为缓释载体的智能降解型微胶囊受到人们越来越多的关注。以MnCO3微粒为模板,采用聚烯丙基胺盐酸盐(PAH)作为壁材,通过层层自组装(LBL)方法得到二硫键交联的聚电解质微胶囊,并对该微胶囊的形貌和化学结构进行了表征分析。结果表明:制备得到微胶囊粒径分布均匀,大小在2.40 μm左右,壁厚约为55.25 nm;具有一定的机械强度,在高浓度的聚苯乙烯磺酸钠(PSS)溶液中会发生可逆弹性形变;傅里叶红外光谱显示,PAH中的部分氨基已经与交联剂3,3′二硫代二丙酸(DPA)中的羧基在EDC/NHS 存在的条件下发生了交联反应,从而形成了比较稳定的囊壁结构。

参考文献/References:

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[2] SIVAKUMAR S, BANSAL V, CORTEZ C. Degradable, surfactantfree, monodisperse polymerencapsulatedemulsions as anticancer drug Carriers [J]. Advanced Materials,2009,21(18):1820-1824.
[3] ZELIKIN A N, BECKER A L, JOHNSTON A P R, et al. A general approach for DNA encapsulation in degradable polymer microcapsules [J]. ACS Nano,2007,1(1):63-69.
[4] KOKER S D, GEEST B D, SINGH S K. Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells:uptake, processing, and crosspresentation of encapsulated antigens [J]. Angewandte Chemie International Edition,2009,48(45):8485-8489.
[5] SEXTON A, WHITNEY P G, CHONG S. Protective vaccine delivery system for in vivo T cell stimulation using nanoengineered polymer hydrogel capsules [J]. ACS Nano,2009,3(11):3391-3400.
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备注/Memo

备注/Memo:
收稿日期: 2016-10-30
网络出版日期: 2017-01-19
基金项目: 国家自然科学基金项目(51603188);浙江省自然科学基金项目(LQ15E030004);浙江理工大学科研启动基金项目(13012141Y)
作者简介: 刘建军(1990-),男,江苏南京人,硕士研究生,主要从事生物医用材料方面的研究。
通信作者: 胡智文,E-mail:zstu17526@126.com
更新日期/Last Update: 2017-09-25